SmartPAN® is a first-in-class indicator aimed at reducing postoperative complications
Biochemical leakage indicator
SmartPAN allows surgeons to visualize pancreatic leakage, for securing complete tissue closure during surgery. It is a first-in class indicator aimed at reducing postoperative complications.
Get To Know SmartPAN®
SmartPAN is a hydrogel of degradable starch microspheres, loaded with bromothymol blue (BTB). BTB represents a pH indicator, that has an orange color in neutral or acidic medium and a blue color in alkaline media.
The color change is detectable with the naked eye and supports the surgeon in the clinical setting by providing a rapid, localized identification of leakage.
Degradable starch microspheres
with pH indicator bound to its
surface and within its matrix.
Immediate color change in reaction
to pancreatic fluid.
SmartPAN is biodegradable
and left over traces are
eliminated from the body.
How does SmartPAN® work?
SmartPAN is applied in one continuous layer to the tissue surface.
SmartPAN appears orange when applied, but locally turns blue over pancreatic
leakage. This indicator reaction happens immediately or within seconds.
When pancreatic leakage becomes visible, targeted closure using surgical means may be performed.
It is recommended that SmartPAN is re-applied after targeted closure to confirm
tightness of the action.
After usage, rinsing of the surgical site and drainage or suctioning of jet fluid should
be assured to avoid accumulation of the product in the abdominal cavity.
SmartPAN is provided sterile, in a pre-filled, single-use applicator. It is ready-to-use and does not need any preparation. Standard applicator contains 10 ml of the product. This amount will allow for repeated application in one patient.
- Visualizes pancreatic leakage immediately on contact with pancreatic fluid.
- Applied easily to the surgical closure site and generates highly visible color indication when in contact with pancreatic fluid, indicating leakage.
- Gives the surgeon confidence that no pancreatic fluid is leakging at time of surgery completion.
- Delivered as a sterile pre-packed syringe, ready to use SmartPAN enables the surgeon to localize pancreatic leakage, to evaluate quantity, and to adapt perioperative management, e.g. to perform targeted closure.
SmartPAN®
- Instantly visualizes pancreatic leakage upon contact with pancreatic fluid, allowing surgeons to identify the leakage area directly.
- Applied easily to the surgical site, providing a highly visible color indication when in contact with pancreatic fluid, Giving the surgeon confidence that no pancreatic fluid is leaking out of the anastomosis at the time of surgery completion.
- Utilizes a patented and well-proven biocompatible and biodegradable microsphere technology (DSM) loaded with pH indicators. Ensuring a color reaction upon contact with the pancreatic fluid.
- SmartPAN was designed and developed together with surgeons for best patient outcomes.
